diff --git a/homeassistant/components/esphome/__init__.py b/homeassistant/components/esphome/__init__.py
index fcfb4cf7ff1..c0c3d02ec56 100644
--- a/homeassistant/components/esphome/__init__.py
+++ b/homeassistant/components/esphome/__init__.py
@@ -225,6 +225,14 @@ async def _setup_auto_reconnect_logic(
             # When removing/disconnecting manually
             return
 
+        device_registry = await hass.helpers.device_registry.async_get_registry()
+        devices = dr.async_entries_for_config_entry(device_registry, entry.entry_id)
+        for device in devices:
+            # There is only one device in ESPHome
+            if device.disabled:
+                # Don't attempt to connect if it's disabled
+                return
+
         data: RuntimeEntryData = hass.data[DOMAIN][entry.entry_id]
         for disconnect_cb in data.disconnect_callbacks:
             disconnect_cb()