diff --git a/homeassistant/package_constraints.txt b/homeassistant/package_constraints.txt
index 630eb789d00..49c1b2df2ff 100644
--- a/homeassistant/package_constraints.txt
+++ b/homeassistant/package_constraints.txt
@@ -8,7 +8,7 @@ attrs==19.3.0
 bcrypt==3.1.7
 certifi>=2020.12.5
 ciso8601==2.1.3
-cryptography==3.2
+cryptography==3.3.1
 defusedxml==0.6.0
 distro==1.5.0
 emoji==0.5.4
diff --git a/requirements.txt b/requirements.txt
index c973f4e4030..ef7d73e1cb5 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -11,7 +11,7 @@ ciso8601==2.1.3
 httpx==0.16.1
 jinja2>=2.11.2
 PyJWT==1.7.1
-cryptography==3.2
+cryptography==3.3.1
 pip>=8.0.3,<20.3
 python-slugify==4.0.1
 pytz>=2020.5
diff --git a/setup.py b/setup.py
index 7f77e3795b4..5998a40a24e 100755
--- a/setup.py
+++ b/setup.py
@@ -43,7 +43,7 @@ REQUIRES = [
     "jinja2>=2.11.2",
     "PyJWT==1.7.1",
     # PyJWT has loose dependency. We want the latest one.
-    "cryptography==3.2",
+    "cryptography==3.3.1",
     "pip>=8.0.3,<20.3",
     "python-slugify==4.0.1",
     "pytz>=2020.5",