diff --git a/.coveragerc b/.coveragerc
index b63c2cbaa1f..d0c15a448f7 100644
--- a/.coveragerc
+++ b/.coveragerc
@@ -1268,6 +1268,7 @@ omit =
     homeassistant/components/waze_travel_time/helpers.py
     homeassistant/components/waze_travel_time/sensor.py
     homeassistant/components/webostv/*
+    homeassistant/components/whois/__init__.py
     homeassistant/components/whois/sensor.py
     homeassistant/components/wiffi/*
     homeassistant/components/wirelesstag/*
diff --git a/CODEOWNERS b/CODEOWNERS
index 2b9c92c5c09..72ec3ae2322 100644
--- a/CODEOWNERS
+++ b/CODEOWNERS
@@ -1035,6 +1035,7 @@ tests/components/wemo/* @esev
 homeassistant/components/whirlpool/* @abmantis
 tests/components/whirlpool/* @abmantis
 homeassistant/components/whois/* @frenck
+tests/components/whois/* @frenck
 homeassistant/components/wiffi/* @mampfes
 tests/components/wiffi/* @mampfes
 homeassistant/components/wilight/* @leofig-rj
diff --git a/homeassistant/components/whois/__init__.py b/homeassistant/components/whois/__init__.py
index 3f3ffefde48..520c9ec0bfe 100644
--- a/homeassistant/components/whois/__init__.py
+++ b/homeassistant/components/whois/__init__.py
@@ -1 +1,16 @@
-"""The whois component."""
+"""The Whois integration."""
+from homeassistant.config_entries import ConfigEntry
+from homeassistant.core import HomeAssistant
+
+from .const import PLATFORMS
+
+
+async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
+    """Set up from a config entry."""
+    hass.config_entries.async_setup_platforms(entry, PLATFORMS)
+    return True
+
+
+async def async_unload_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
+    """Unload a config entry."""
+    return await hass.config_entries.async_unload_platforms(entry, PLATFORMS)
diff --git a/homeassistant/components/whois/config_flow.py b/homeassistant/components/whois/config_flow.py
new file mode 100644
index 00000000000..0f030a2b9b7
--- /dev/null
+++ b/homeassistant/components/whois/config_flow.py
@@ -0,0 +1,52 @@
+"""Config flow to configure the Whois integration."""
+from __future__ import annotations
+
+from typing import Any
+
+import voluptuous as vol
+
+from homeassistant.config_entries import ConfigFlow
+from homeassistant.const import CONF_DOMAIN, CONF_NAME
+from homeassistant.data_entry_flow import FlowResult
+
+from .const import DOMAIN
+
+
+class WhoisFlowHandler(ConfigFlow, domain=DOMAIN):
+    """Config flow for Whois."""
+
+    VERSION = 1
+
+    imported_name: str | None = None
+
+    async def async_step_user(
+        self, user_input: dict[str, Any] | None = None
+    ) -> FlowResult:
+        """Handle a flow initialized by the user."""
+        if user_input is not None:
+            await self.async_set_unique_id(user_input[CONF_DOMAIN].lower())
+            self._abort_if_unique_id_configured()
+            return self.async_create_entry(
+                title=self.imported_name or user_input[CONF_DOMAIN],
+                data={
+                    CONF_DOMAIN: user_input[CONF_DOMAIN].lower(),
+                },
+            )
+
+        return self.async_show_form(
+            step_id="user",
+            data_schema=vol.Schema(
+                {
+                    vol.Required(CONF_DOMAIN): str,
+                }
+            ),
+        )
+
+    async def async_step_import(self, config: dict[str, Any]) -> FlowResult:
+        """Handle a flow initialized by importing a config."""
+        self.imported_name = config[CONF_NAME]
+        return await self.async_step_user(
+            user_input={
+                CONF_DOMAIN: config[CONF_DOMAIN],
+            }
+        )
diff --git a/homeassistant/components/whois/const.py b/homeassistant/components/whois/const.py
index 7210ada91a2..b48fc3e1fee 100644
--- a/homeassistant/components/whois/const.py
+++ b/homeassistant/components/whois/const.py
@@ -4,7 +4,10 @@ from __future__ import annotations
 import logging
 from typing import Final
 
+from homeassistant.const import Platform
+
 DOMAIN: Final = "whois"
+PLATFORMS = [Platform.SENSOR]
 
 LOGGER = logging.getLogger(__package__)
 
diff --git a/homeassistant/components/whois/manifest.json b/homeassistant/components/whois/manifest.json
index 6da78b32b7f..64922252565 100644
--- a/homeassistant/components/whois/manifest.json
+++ b/homeassistant/components/whois/manifest.json
@@ -3,6 +3,7 @@
   "name": "Whois",
   "documentation": "https://www.home-assistant.io/integrations/whois",
   "requirements": ["python-whois==0.7.3"],
+  "config_flow": true,
   "codeowners": ["@frenck"],
   "iot_class": "cloud_polling"
 }
diff --git a/homeassistant/components/whois/sensor.py b/homeassistant/components/whois/sensor.py
index febdc68aa8c..2848e27e868 100644
--- a/homeassistant/components/whois/sensor.py
+++ b/homeassistant/components/whois/sensor.py
@@ -7,6 +7,7 @@ import voluptuous as vol
 import whois
 
 from homeassistant.components.sensor import PLATFORM_SCHEMA, SensorEntity
+from homeassistant.config_entries import SOURCE_IMPORT, ConfigEntry
 from homeassistant.const import CONF_DOMAIN, CONF_NAME, TIME_DAYS
 from homeassistant.core import HomeAssistant
 import homeassistant.helpers.config_validation as cv
@@ -19,10 +20,11 @@ from .const import (
     ATTR_REGISTRAR,
     ATTR_UPDATED,
     DEFAULT_NAME,
+    DOMAIN,
     LOGGER,
 )
 
-SCANTERVAL = timedelta(hours=24)
+SCAN_INTERVAL = timedelta(hours=24)
 
 PLATFORM_SCHEMA = PLATFORM_SCHEMA.extend(
     {
@@ -39,21 +41,40 @@ def setup_platform(
     discovery_info: DiscoveryInfoType | None = None,
 ) -> None:
     """Set up the WHOIS sensor."""
-    domain = config[CONF_DOMAIN]
-    name = config[CONF_NAME]
+    LOGGER.warning(
+        "Configuration of the Whois platform in YAML is deprecated and will be "
+        "removed in Home Assistant 2022.4; Your existing configuration "
+        "has been imported into the UI automatically and can be safely removed "
+        "from your configuration.yaml file"
+    )
+    hass.async_create_task(
+        hass.config_entries.flow.async_init(
+            DOMAIN,
+            context={"source": SOURCE_IMPORT},
+            data={CONF_DOMAIN: config[CONF_DOMAIN], CONF_NAME: config[CONF_NAME]},
+        )
+    )
 
+
+async def async_setup_entry(
+    hass: HomeAssistant,
+    entry: ConfigEntry,
+    async_add_entities: AddEntitiesCallback,
+) -> None:
+    """Set up the platform from config_entry."""
+    domain = entry.data[CONF_DOMAIN]
     try:
-        if "expiration_date" in whois.whois(domain):
-            add_entities([WhoisSensor(name, domain)], True)
-        else:
-            LOGGER.error(
-                "WHOIS lookup for %s didn't contain an expiration date", domain
-            )
-            return
+        info = await hass.async_add_executor_job(whois.whois, domain)
     except whois.BaseException as ex:  # pylint: disable=broad-except
         LOGGER.error("Exception %s occurred during WHOIS lookup for %s", ex, domain)
         return
 
+    if "expiration_date" not in info:
+        LOGGER.error("WHOIS lookup for %s didn't contain an expiration date", domain)
+        return
+
+    async_add_entities([WhoisSensor(domain)], True)
+
 
 class WhoisSensor(SensorEntity):
     """Implementation of a WHOIS sensor."""
@@ -61,11 +82,11 @@ class WhoisSensor(SensorEntity):
     _attr_icon = "mdi:calendar-clock"
     _attr_native_unit_of_measurement = TIME_DAYS
 
-    def __init__(self, name: str, domain: str) -> None:
+    def __init__(self, domain: str) -> None:
         """Initialize the sensor."""
+        self._attr_name = domain
         self.whois = whois.whois
         self._domain = domain
-        self._attr_name = name
 
     def _empty_value_and_attributes(self) -> None:
         """Empty the state and attributes on an error."""
diff --git a/homeassistant/components/whois/strings.json b/homeassistant/components/whois/strings.json
new file mode 100644
index 00000000000..bdd1375aee3
--- /dev/null
+++ b/homeassistant/components/whois/strings.json
@@ -0,0 +1,14 @@
+{
+  "config": {
+    "step": {
+      "user": {
+        "data": {
+          "domain": "Domain name"
+        }
+      }
+    },
+    "abort": {
+      "already_configured": "[%key:common::config_flow::abort::already_configured_service%]"
+    }
+  }
+}
diff --git a/homeassistant/components/whois/translations/en.json b/homeassistant/components/whois/translations/en.json
new file mode 100644
index 00000000000..8379ebe9579
--- /dev/null
+++ b/homeassistant/components/whois/translations/en.json
@@ -0,0 +1,14 @@
+{
+    "config": {
+        "abort": {
+            "already_configured": "Service is already configured"
+        },
+        "step": {
+            "user": {
+                "data": {
+                    "domain": "Domain name"
+                }
+            }
+        }
+    }
+}
\ No newline at end of file
diff --git a/homeassistant/generated/config_flows.py b/homeassistant/generated/config_flows.py
index c8888adbbd5..cd78d54a3bb 100644
--- a/homeassistant/generated/config_flows.py
+++ b/homeassistant/generated/config_flows.py
@@ -347,6 +347,7 @@ FLOWS = [
     "waze_travel_time",
     "wemo",
     "whirlpool",
+    "whois",
     "wiffi",
     "wilight",
     "withings",
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index 29862d79fec..251f39779ef 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -1193,6 +1193,9 @@ python-tado==0.12.0
 # homeassistant.components.twitch
 python-twitch-client==0.6.0
 
+# homeassistant.components.whois
+python-whois==0.7.3
+
 # homeassistant.components.awair
 python_awair==0.2.1
 
diff --git a/tests/components/whois/__init__.py b/tests/components/whois/__init__.py
new file mode 100644
index 00000000000..753779d0f40
--- /dev/null
+++ b/tests/components/whois/__init__.py
@@ -0,0 +1 @@
+"""Tests for the Whois integration."""
diff --git a/tests/components/whois/conftest.py b/tests/components/whois/conftest.py
new file mode 100644
index 00000000000..ca9b123f491
--- /dev/null
+++ b/tests/components/whois/conftest.py
@@ -0,0 +1,34 @@
+"""Fixtures for Whois integration tests."""
+from __future__ import annotations
+
+from collections.abc import Generator
+from unittest.mock import AsyncMock, patch
+
+import pytest
+
+from homeassistant.components.whois.const import DOMAIN
+from homeassistant.const import CONF_DOMAIN
+
+from tests.common import MockConfigEntry
+
+
+@pytest.fixture
+def mock_config_entry() -> MockConfigEntry:
+    """Return the default mocked config entry."""
+    return MockConfigEntry(
+        title="Home Assistant",
+        domain=DOMAIN,
+        data={
+            CONF_DOMAIN: "Home-Assistant.io",
+        },
+        unique_id="home-assistant.io",
+    )
+
+
+@pytest.fixture
+def mock_setup_entry() -> Generator[AsyncMock, None, None]:
+    """Mock setting up a config entry."""
+    with patch(
+        "homeassistant.components.whois.async_setup_entry", return_value=True
+    ) as mock_setup:
+        yield mock_setup
diff --git a/tests/components/whois/test_config_flow.py b/tests/components/whois/test_config_flow.py
new file mode 100644
index 00000000000..71cc195c407
--- /dev/null
+++ b/tests/components/whois/test_config_flow.py
@@ -0,0 +1,80 @@
+"""Tests for the Whois config flow."""
+
+from unittest.mock import AsyncMock
+
+from homeassistant.components.whois.const import DOMAIN
+from homeassistant.config_entries import SOURCE_IMPORT, SOURCE_USER
+from homeassistant.const import CONF_DOMAIN, CONF_NAME
+from homeassistant.core import HomeAssistant
+from homeassistant.data_entry_flow import (
+    RESULT_TYPE_ABORT,
+    RESULT_TYPE_CREATE_ENTRY,
+    RESULT_TYPE_FORM,
+)
+
+from tests.common import MockConfigEntry
+
+
+async def test_full_user_flow(
+    hass: HomeAssistant,
+    mock_setup_entry: AsyncMock,
+) -> None:
+    """Test the full user configuration flow."""
+    result = await hass.config_entries.flow.async_init(
+        DOMAIN, context={"source": SOURCE_USER}
+    )
+
+    assert result.get("type") == RESULT_TYPE_FORM
+    assert result.get("step_id") == SOURCE_USER
+    assert "flow_id" in result
+
+    result2 = await hass.config_entries.flow.async_configure(
+        result["flow_id"],
+        user_input={CONF_DOMAIN: "Example.com"},
+    )
+
+    assert result2.get("type") == RESULT_TYPE_CREATE_ENTRY
+    assert result2.get("title") == "Example.com"
+    assert result2.get("data") == {CONF_DOMAIN: "example.com"}
+
+    assert len(mock_setup_entry.mock_calls) == 1
+
+
+async def test_already_configured(
+    hass: HomeAssistant,
+    mock_setup_entry: AsyncMock,
+    mock_config_entry: MockConfigEntry,
+) -> None:
+    """Test we abort if already configured."""
+    mock_config_entry.add_to_hass(hass)
+
+    result = await hass.config_entries.flow.async_init(
+        DOMAIN,
+        context={"source": SOURCE_USER},
+        data={CONF_DOMAIN: "HOME-Assistant.io"},
+    )
+
+    assert result.get("type") == RESULT_TYPE_ABORT
+    assert result.get("reason") == "already_configured"
+
+    assert len(mock_setup_entry.mock_calls) == 0
+
+
+async def test_import_flow(
+    hass: HomeAssistant,
+    mock_setup_entry: AsyncMock,
+) -> None:
+    """Test the import configuration flow."""
+    result = await hass.config_entries.flow.async_init(
+        DOMAIN,
+        context={"source": SOURCE_IMPORT},
+        data={CONF_DOMAIN: "Example.com", CONF_NAME: "My Example Domain"},
+    )
+
+    assert result.get("type") == RESULT_TYPE_CREATE_ENTRY
+    assert result.get("title") == "My Example Domain"
+    assert result.get("data") == {
+        CONF_DOMAIN: "example.com",
+    }
+
+    assert len(mock_setup_entry.mock_calls) == 1