diff --git a/homeassistant/helpers/dispatcher.py b/homeassistant/helpers/dispatcher.py
index 60aab156144..e416d939914 100644
--- a/homeassistant/helpers/dispatcher.py
+++ b/homeassistant/helpers/dispatcher.py
@@ -2,6 +2,7 @@
 from __future__ import annotations
 
 from collections.abc import Callable, Coroutine
+from functools import partial
 import logging
 from typing import Any
 
@@ -13,6 +14,14 @@ from homeassistant.util.logging import catch_log_exception
 _LOGGER = logging.getLogger(__name__)
 DATA_DISPATCHER = "dispatcher"
 
+_DispatcherDataType = dict[
+    str,
+    dict[
+        Callable[..., Any],
+        HassJob[..., None | Coroutine[Any, Any, None]] | None,
+    ],
+]
+
 
 @bind_hass
 def dispatcher_connect(
@@ -30,6 +39,26 @@ def dispatcher_connect(
     return remove_dispatcher
 
 
+@callback
+def _async_remove_dispatcher(
+    dispatchers: _DispatcherDataType,
+    signal: str,
+    target: Callable[..., Any],
+) -> None:
+    """Remove signal listener."""
+    try:
+        signal_dispatchers = dispatchers[signal]
+        del signal_dispatchers[target]
+        # Cleanup the signal dict if it is now empty
+        # to prevent memory leaks
+        if not signal_dispatchers:
+            del dispatchers[signal]
+    except (KeyError, ValueError):
+        # KeyError is key target listener did not exist
+        # ValueError if listener did not exist within signal
+        _LOGGER.warning("Unable to remove unknown dispatcher %s", target)
+
+
 @callback
 @bind_hass
 def async_dispatcher_connect(
@@ -41,19 +70,18 @@ def async_dispatcher_connect(
     """
     if DATA_DISPATCHER not in hass.data:
         hass.data[DATA_DISPATCHER] = {}
-    hass.data[DATA_DISPATCHER].setdefault(signal, {})[target] = None
 
-    @callback
-    def async_remove_dispatcher() -> None:
-        """Remove signal listener."""
-        try:
-            del hass.data[DATA_DISPATCHER][signal][target]
-        except (KeyError, ValueError):
-            # KeyError is key target listener did not exist
-            # ValueError if listener did not exist within signal
-            _LOGGER.warning("Unable to remove unknown dispatcher %s", target)
+    dispatchers: _DispatcherDataType = hass.data[DATA_DISPATCHER]
 
-    return async_remove_dispatcher
+    if signal not in dispatchers:
+        dispatchers[signal] = {}
+
+    dispatchers[signal][target] = None
+    # Use a partial for the remove since it uses
+    # less memory than a full closure since a partial copies
+    # the body of the function and we don't have to store
+    # many different copies of the same function
+    return partial(_async_remove_dispatcher, dispatchers, signal, target)
 
 
 @bind_hass
@@ -87,21 +115,14 @@ def async_dispatcher_send(hass: HomeAssistant, signal: str, *args: Any) -> None:
 
     This method must be run in the event loop.
     """
-    target_list: dict[
-        Callable[..., Any], HassJob[..., None | Coroutine[Any, Any, None]] | None
-    ] = hass.data.get(DATA_DISPATCHER, {}).get(signal, {})
+    if (maybe_dispatchers := hass.data.get(DATA_DISPATCHER)) is None:
+        return
+    dispatchers: _DispatcherDataType = maybe_dispatchers
+    if (target_list := dispatchers.get(signal)) is None:
+        return
 
-    run: list[HassJob[..., None | Coroutine[Any, Any, None]]] = []
-    for target, job in target_list.items():
+    for target, job in list(target_list.items()):
         if job is None:
             job = _generate_job(signal, target)
             target_list[target] = job
-
-        # Run the jobs all at the end
-        # to ensure no jobs add more dispatchers
-        # which can result in the target_list
-        # changing size during iteration
-        run.append(job)
-
-    for job in run:
         hass.async_run_hass_job(job, *args)
diff --git a/tests/helpers/test_dispatcher.py b/tests/helpers/test_dispatcher.py
index e30aaa6e0d9..a251b20b0f4 100644
--- a/tests/helpers/test_dispatcher.py
+++ b/tests/helpers/test_dispatcher.py
@@ -151,3 +151,25 @@ async def test_callback_exception_gets_logged(
         f"Exception in functools.partial({bad_handler}) when dispatching 'test': ('bad',)"
         in caplog.text
     )
+
+
+async def test_dispatcher_add_dispatcher(hass: HomeAssistant) -> None:
+    """Test adding a dispatcher from a dispatcher."""
+    calls = []
+
+    @callback
+    def _new_dispatcher(data):
+        calls.append(data)
+
+    @callback
+    def _add_new_dispatcher(data):
+        calls.append(data)
+        async_dispatcher_connect(hass, "test", _new_dispatcher)
+
+    async_dispatcher_connect(hass, "test", _add_new_dispatcher)
+
+    async_dispatcher_send(hass, "test", 3)
+    async_dispatcher_send(hass, "test", 4)
+    async_dispatcher_send(hass, "test", 5)
+
+    assert calls == [3, 4, 4, 5, 5]