diff --git a/homeassistant/helpers/issue_registry.py b/homeassistant/helpers/issue_registry.py
index 11bde0edf6b..49dc2a36cb0 100644
--- a/homeassistant/helpers/issue_registry.py
+++ b/homeassistant/helpers/issue_registry.py
@@ -132,7 +132,7 @@ class IssueRegistry(BaseRegistry):
         translation_placeholders: dict[str, str] | None = None,
     ) -> IssueEntry:
         """Get issue. Create if it doesn't exist."""
-
+        self.hass.verify_event_loop_thread("async_get_or_create")
         if (issue := self.async_get_issue(domain, issue_id)) is None:
             issue = IssueEntry(
                 active=True,
@@ -152,7 +152,7 @@ class IssueRegistry(BaseRegistry):
             )
             self.issues[(domain, issue_id)] = issue
             self.async_schedule_save()
-            self.hass.bus.async_fire(
+            self.hass.bus.async_fire_internal(
                 EVENT_REPAIRS_ISSUE_REGISTRY_UPDATED,
                 {"action": "create", "domain": domain, "issue_id": issue_id},
             )
@@ -174,7 +174,7 @@ class IssueRegistry(BaseRegistry):
             if replacement != issue:
                 issue = self.issues[(domain, issue_id)] = replacement
                 self.async_schedule_save()
-                self.hass.bus.async_fire(
+                self.hass.bus.async_fire_internal(
                     EVENT_REPAIRS_ISSUE_REGISTRY_UPDATED,
                     {"action": "update", "domain": domain, "issue_id": issue_id},
                 )
@@ -184,11 +184,12 @@ class IssueRegistry(BaseRegistry):
     @callback
     def async_delete(self, domain: str, issue_id: str) -> None:
         """Delete issue."""
+        self.hass.verify_event_loop_thread("async_delete")
         if self.issues.pop((domain, issue_id), None) is None:
             return
 
         self.async_schedule_save()
-        self.hass.bus.async_fire(
+        self.hass.bus.async_fire_internal(
             EVENT_REPAIRS_ISSUE_REGISTRY_UPDATED,
             {"action": "remove", "domain": domain, "issue_id": issue_id},
         )
@@ -196,6 +197,7 @@ class IssueRegistry(BaseRegistry):
     @callback
     def async_ignore(self, domain: str, issue_id: str, ignore: bool) -> IssueEntry:
         """Ignore issue."""
+        self.hass.verify_event_loop_thread("async_ignore")
         old = self.issues[(domain, issue_id)]
         dismissed_version = ha_version if ignore else None
         if old.dismissed_version == dismissed_version:
@@ -207,7 +209,7 @@ class IssueRegistry(BaseRegistry):
         )
 
         self.async_schedule_save()
-        self.hass.bus.async_fire(
+        self.hass.bus.async_fire_internal(
             EVENT_REPAIRS_ISSUE_REGISTRY_UPDATED,
             {"action": "update", "domain": domain, "issue_id": issue_id},
         )
diff --git a/tests/helpers/test_issue_registry.py b/tests/helpers/test_issue_registry.py
index 66fc9662f75..eb6a32540e9 100644
--- a/tests/helpers/test_issue_registry.py
+++ b/tests/helpers/test_issue_registry.py
@@ -1,5 +1,6 @@
 """Test the repairs websocket API."""
 
+from functools import partial
 from typing import Any
 
 import pytest
@@ -358,3 +359,71 @@ async def test_migration_1_1(hass: HomeAssistant, hass_storage: dict[str, Any])
 
     registry: ir.IssueRegistry = hass.data[ir.DATA_REGISTRY]
     assert len(registry.issues) == 2
+
+
+async def test_get_or_create_thread_safety(
+    hass: HomeAssistant, issue_registry: ir.IssueRegistry
+) -> None:
+    """Test call async_get_or_create_from a thread."""
+    with pytest.raises(
+        RuntimeError,
+        match="Detected code that calls async_get_or_create from a thread. Please report this issue.",
+    ):
+        await hass.async_add_executor_job(
+            partial(
+                ir.async_create_issue,
+                hass,
+                "any",
+                "any",
+                is_fixable=True,
+                severity="error",
+                translation_key="any",
+            )
+        )
+
+
+async def test_async_delete_issue_thread_safety(
+    hass: HomeAssistant, issue_registry: ir.IssueRegistry
+) -> None:
+    """Test call async_delete_issue from a thread."""
+    ir.async_create_issue(
+        hass,
+        "any",
+        "any",
+        is_fixable=True,
+        severity="error",
+        translation_key="any",
+    )
+
+    with pytest.raises(
+        RuntimeError,
+        match="Detected code that calls async_delete from a thread. Please report this issue.",
+    ):
+        await hass.async_add_executor_job(
+            ir.async_delete_issue,
+            hass,
+            "any",
+            "any",
+        )
+
+
+async def test_async_ignore_issue_thread_safety(
+    hass: HomeAssistant, issue_registry: ir.IssueRegistry
+) -> None:
+    """Test call async_ignore_issue from a thread."""
+    ir.async_create_issue(
+        hass,
+        "any",
+        "any",
+        is_fixable=True,
+        severity="error",
+        translation_key="any",
+    )
+
+    with pytest.raises(
+        RuntimeError,
+        match="Detected code that calls async_ignore from a thread. Please report this issue.",
+    ):
+        await hass.async_add_executor_job(
+            ir.async_ignore_issue, hass, "any", "any", True
+        )