diff --git a/homeassistant/components/modbus/__init__.py b/homeassistant/components/modbus/__init__.py
index 09112e16767..d008f5d167c 100644
--- a/homeassistant/components/modbus/__init__.py
+++ b/homeassistant/components/modbus/__init__.py
@@ -97,7 +97,6 @@ from .const import (  # noqa: F401
     CONF_PARITY,
     CONF_PRECISION,
     CONF_RETRIES,
-    CONF_RETRY_ON_EMPTY,
     CONF_SCALE,
     CONF_SLAVE_COUNT,
     CONF_STATE_CLOSED,
@@ -375,7 +374,6 @@ MODBUS_SCHEMA = vol.Schema(
         vol.Optional(CONF_TIMEOUT, default=3): cv.socket_timeout,
         vol.Optional(CONF_DELAY, default=0): cv.positive_int,
         vol.Optional(CONF_RETRIES): cv.positive_int,
-        vol.Optional(CONF_RETRY_ON_EMPTY): cv.boolean,
         vol.Optional(CONF_MSG_WAIT): cv.positive_int,
         vol.Optional(CONF_BINARY_SENSORS): vol.All(
             cv.ensure_list, [BINARY_SENSOR_SCHEMA]
diff --git a/homeassistant/components/modbus/const.py b/homeassistant/components/modbus/const.py
index 3a7b25ad786..425bd744a1e 100644
--- a/homeassistant/components/modbus/const.py
+++ b/homeassistant/components/modbus/const.py
@@ -29,7 +29,6 @@ CONF_MSG_WAIT = "message_wait_milliseconds"
 CONF_NAN_VALUE = "nan_value"
 CONF_PARITY = "parity"
 CONF_RETRIES = "retries"
-CONF_RETRY_ON_EMPTY = "retry_on_empty"
 CONF_PRECISION = "precision"
 CONF_SCALE = "scale"
 CONF_SLAVE_COUNT = "slave_count"
diff --git a/homeassistant/components/modbus/modbus.py b/homeassistant/components/modbus/modbus.py
index 36c081df616..7138341d445 100644
--- a/homeassistant/components/modbus/modbus.py
+++ b/homeassistant/components/modbus/modbus.py
@@ -54,7 +54,6 @@ from .const import (
     CONF_MSG_WAIT,
     CONF_PARITY,
     CONF_RETRIES,
-    CONF_RETRY_ON_EMPTY,
     CONF_STOPBITS,
     DEFAULT_HUB,
     MODBUS_DOMAIN as DOMAIN,
@@ -272,24 +271,6 @@ class ModbusHub:
             )
         else:
             client_config[CONF_RETRIES] = 3
-        if CONF_RETRY_ON_EMPTY in client_config:
-            async_create_issue(
-                hass,
-                DOMAIN,
-                "deprecated_retry_on_empty",
-                breaks_in_ha_version="2024.4.0",
-                is_fixable=False,
-                severity=IssueSeverity.WARNING,
-                translation_key="deprecated_retry_on_empty",
-                translation_placeholders={
-                    "config_key": "retry_on_empty",
-                    "integration": DOMAIN,
-                    "url": "https://www.home-assistant.io/integrations/modbus",
-                },
-            )
-            _LOGGER.warning(
-                "`retry_on_empty`: is deprecated and will be removed in version 2024.4"
-            )
         # generic configuration
         self._client: ModbusBaseClient | None = None
         self._async_cancel_listener: Callable[[], None] | None = None
diff --git a/homeassistant/components/modbus/strings.json b/homeassistant/components/modbus/strings.json
index 12023579669..4f7bb1c60e3 100644
--- a/homeassistant/components/modbus/strings.json
+++ b/homeassistant/components/modbus/strings.json
@@ -77,10 +77,6 @@
     "deprecated_retries": {
       "title": "`{config_key}` configuration key is being removed",
       "description": "Please remove the `{config_key}` key from the {integration} entry in your configuration.yaml file and restart Home Assistant to fix this issue.\n\nThe maximum number of retries is now fixed to 3."
-    },
-    "deprecated_retry_on_empty": {
-      "title": "`{config_key}` configuration key is being removed",
-      "description": "Please remove the `{config_key}` key from the {integration} entry in your configuration.yaml file and restart Home Assistant to fix this issue.\n\nRetry on empty is automatically applied, see [the documentation]({url}) for other error handling parameters."
     }
   }
 }
diff --git a/tests/components/modbus/test_init.py b/tests/components/modbus/test_init.py
index 20eecf49591..aaf2b335b90 100644
--- a/tests/components/modbus/test_init.py
+++ b/tests/components/modbus/test_init.py
@@ -60,7 +60,6 @@ from homeassistant.components.modbus.const import (
     CONF_MSG_WAIT,
     CONF_PARITY,
     CONF_RETRIES,
-    CONF_RETRY_ON_EMPTY,
     CONF_SLAVE_COUNT,
     CONF_STOPBITS,
     CONF_SWAP,
@@ -974,7 +973,6 @@ async def test_no_duplicate_names(do_config) -> None:
             CONF_TYPE: TCP,
             CONF_HOST: TEST_MODBUS_HOST,
             CONF_PORT: TEST_PORT_TCP,
-            CONF_RETRY_ON_EMPTY: True,
         },
         {
             CONF_TYPE: TCP,