diff --git a/homeassistant/components/accuweather/__init__.py b/homeassistant/components/accuweather/__init__.py
index b2ec7e0224b..90b939ab3b9 100644
--- a/homeassistant/components/accuweather/__init__.py
+++ b/homeassistant/components/accuweather/__init__.py
@@ -8,7 +8,6 @@ from aiohttp.client_exceptions import ClientConnectorError
 from async_timeout import timeout
 
 from homeassistant.const import CONF_API_KEY
-from homeassistant.core import Config, HomeAssistant
 from homeassistant.exceptions import ConfigEntryNotReady
 from homeassistant.helpers.aiohttp_client import async_get_clientsession
 from homeassistant.helpers.update_coordinator import DataUpdateCoordinator, UpdateFailed
@@ -26,12 +25,6 @@ _LOGGER = logging.getLogger(__name__)
 PLATFORMS = ["sensor", "weather"]
 
 
-async def async_setup(hass: HomeAssistant, config: Config) -> bool:
-    """Set up configured AccuWeather."""
-    hass.data.setdefault(DOMAIN, {})
-    return True
-
-
 async def async_setup_entry(hass, config_entry) -> bool:
     """Set up AccuWeather as config entry."""
     api_key = config_entry.data[CONF_API_KEY]
@@ -52,7 +45,7 @@ async def async_setup_entry(hass, config_entry) -> bool:
 
     undo_listener = config_entry.add_update_listener(update_listener)
 
-    hass.data[DOMAIN][config_entry.entry_id] = {
+    hass.data.setdefault(DOMAIN, {})[config_entry.entry_id] = {
         COORDINATOR: coordinator,
         UNDO_UPDATE_LISTENER: undo_listener,
     }
diff --git a/homeassistant/components/adguard/__init__.py b/homeassistant/components/adguard/__init__.py
index 04d266e7d9b..0f10d20ec59 100644
--- a/homeassistant/components/adguard/__init__.py
+++ b/homeassistant/components/adguard/__init__.py
@@ -34,7 +34,6 @@ from homeassistant.exceptions import ConfigEntryNotReady
 from homeassistant.helpers import config_validation as cv
 from homeassistant.helpers.aiohttp_client import async_get_clientsession
 from homeassistant.helpers.entity import Entity
-from homeassistant.helpers.typing import ConfigType
 
 _LOGGER = logging.getLogger(__name__)
 
@@ -49,11 +48,6 @@ SERVICE_REFRESH_SCHEMA = vol.Schema(
 PLATFORMS = ["sensor", "switch"]
 
 
-async def async_setup(hass: HomeAssistant, config: ConfigType) -> bool:
-    """Set up the AdGuard Home components."""
-    return True
-
-
 async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
     """Set up AdGuard Home from a config entry."""
     session = async_get_clientsession(hass, entry.data[CONF_VERIFY_SSL])
diff --git a/homeassistant/components/airnow/__init__.py b/homeassistant/components/airnow/__init__.py
index 1732445c566..04e1567e067 100644
--- a/homeassistant/components/airnow/__init__.py
+++ b/homeassistant/components/airnow/__init__.py
@@ -38,11 +38,6 @@ _LOGGER = logging.getLogger(__name__)
 PLATFORMS = ["sensor"]
 
 
-async def async_setup(hass: HomeAssistant, config: dict):
-    """Set up the AirNow component."""
-    return True
-
-
 async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry):
     """Set up AirNow from a config entry."""
     api_key = entry.data[CONF_API_KEY]
diff --git a/homeassistant/components/deconz/__init__.py b/homeassistant/components/deconz/__init__.py
index 1b8c47d36a2..8b609fe3126 100644
--- a/homeassistant/components/deconz/__init__.py
+++ b/homeassistant/components/deconz/__init__.py
@@ -20,11 +20,6 @@ CONFIG_SCHEMA = vol.Schema(
 )
 
 
-async def async_setup(hass, config):
-    """Old way of setting up deCONZ integrations."""
-    return True
-
-
 async def async_setup_entry(hass, config_entry):
     """Set up a deCONZ bridge for a config entry.
 
diff --git a/homeassistant/components/elgato/__init__.py b/homeassistant/components/elgato/__init__.py
index 4f7731c122d..22d60406780 100644
--- a/homeassistant/components/elgato/__init__.py
+++ b/homeassistant/components/elgato/__init__.py
@@ -9,16 +9,10 @@ from homeassistant.const import CONF_HOST, CONF_PORT
 from homeassistant.core import HomeAssistant
 from homeassistant.exceptions import ConfigEntryNotReady
 from homeassistant.helpers.aiohttp_client import async_get_clientsession
-from homeassistant.helpers.typing import ConfigType
 
 from .const import DATA_ELGATO_CLIENT, DOMAIN
 
 
-async def async_setup(hass: HomeAssistant, config: ConfigType) -> bool:
-    """Set up the Elgato Key Light components."""
-    return True
-
-
 async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
     """Set up Elgato Key Light from a config entry."""
     session = async_get_clientsession(hass)
diff --git a/homeassistant/components/esphome/__init__.py b/homeassistant/components/esphome/__init__.py
index 0cb6cd94e08..02d6309fe7f 100644
--- a/homeassistant/components/esphome/__init__.py
+++ b/homeassistant/components/esphome/__init__.py
@@ -42,7 +42,7 @@ from homeassistant.helpers.json import JSONEncoder
 from homeassistant.helpers.service import async_set_service_schema
 from homeassistant.helpers.storage import Store
 from homeassistant.helpers.template import Template
-from homeassistant.helpers.typing import ConfigType, HomeAssistantType
+from homeassistant.helpers.typing import HomeAssistantType
 
 # Import config flow so that it's added to the registry
 from .entry_data import RuntimeEntryData
@@ -56,11 +56,6 @@ STORAGE_VERSION = 1
 CONFIG_SCHEMA = vol.Schema({}, extra=vol.ALLOW_EXTRA)
 
 
-async def async_setup(hass: HomeAssistantType, config: ConfigType) -> bool:
-    """Stub to allow setting up this component."""
-    return True
-
-
 async def async_setup_entry(hass: HomeAssistantType, entry: ConfigEntry) -> bool:
     """Set up the esphome component."""
     hass.data.setdefault(DOMAIN, {})
diff --git a/homeassistant/components/tasmota/__init__.py b/homeassistant/components/tasmota/__init__.py
index 0b42725cdcf..83baae9c19c 100644
--- a/homeassistant/components/tasmota/__init__.py
+++ b/homeassistant/components/tasmota/__init__.py
@@ -24,7 +24,6 @@ from homeassistant.helpers.device_registry import (
     EVENT_DEVICE_REGISTRY_UPDATED,
     async_entries_for_config_entry,
 )
-from homeassistant.helpers.typing import HomeAssistantType
 
 from . import device_automation, discovery
 from .const import (
@@ -38,11 +37,6 @@ from .const import (
 _LOGGER = logging.getLogger(__name__)
 
 
-async def async_setup(hass: HomeAssistantType, config: dict):
-    """Set up the Tasmota component."""
-    return True
-
-
 async def async_setup_entry(hass, entry):
     """Set up Tasmota from a config entry."""
     websocket_api.async_register_command(hass, websocket_remove_device)
diff --git a/homeassistant/components/wled/__init__.py b/homeassistant/components/wled/__init__.py
index 2ec02931415..069c12a2d06 100644
--- a/homeassistant/components/wled/__init__.py
+++ b/homeassistant/components/wled/__init__.py
@@ -16,7 +16,6 @@ from homeassistant.const import ATTR_NAME, CONF_HOST
 from homeassistant.core import HomeAssistant
 from homeassistant.exceptions import ConfigEntryNotReady
 from homeassistant.helpers.aiohttp_client import async_get_clientsession
-from homeassistant.helpers.typing import ConfigType
 from homeassistant.helpers.update_coordinator import (
     CoordinatorEntity,
     DataUpdateCoordinator,
@@ -37,11 +36,6 @@ PLATFORMS = (LIGHT_DOMAIN, SENSOR_DOMAIN, SWITCH_DOMAIN)
 _LOGGER = logging.getLogger(__name__)
 
 
-async def async_setup(hass: HomeAssistant, config: ConfigType) -> bool:
-    """Set up the WLED components."""
-    return True
-
-
 async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
     """Set up WLED from a config entry."""
 
diff --git a/homeassistant/setup.py b/homeassistant/setup.py
index 288f9d0847b..6b306995dfc 100644
--- a/homeassistant/setup.py
+++ b/homeassistant/setup.py
@@ -169,7 +169,7 @@ async def _async_setup_component(
         return False
 
     if integration.disabled:
-        log_error(f"dependency is disabled - {integration.disabled}")
+        log_error(f"Dependency is disabled - {integration.disabled}")
         return False
 
     # Validate all dependencies exist and there are no circular dependencies
@@ -219,6 +219,8 @@ async def _async_setup_component(
             SLOW_SETUP_WARNING,
         )
 
+    task = None
+    result = True
     try:
         if hasattr(component, "async_setup"):
             task = component.async_setup(hass, processed_config)  # type: ignore
@@ -228,13 +230,14 @@ async def _async_setup_component(
             task = hass.loop.run_in_executor(
                 None, component.setup, hass, processed_config  # type: ignore
             )
-        else:
-            log_error("No setup function defined.")
+        elif not hasattr(component, "async_setup_entry"):
+            log_error("No setup or config entry setup function defined.")
             hass.data[DATA_SETUP_STARTED].pop(domain)
             return False
 
-        async with hass.timeout.async_timeout(SLOW_SETUP_MAX_WAIT, domain):
-            result = await task
+        if task:
+            async with hass.timeout.async_timeout(SLOW_SETUP_MAX_WAIT, domain):
+                result = await task
     except asyncio.TimeoutError:
         _LOGGER.error(
             "Setup of %s is taking longer than %s seconds."
diff --git a/script/scaffold/templates/config_flow/integration/__init__.py b/script/scaffold/templates/config_flow/integration/__init__.py
index 24a0c1d7350..6c187d1dafe 100644
--- a/script/scaffold/templates/config_flow/integration/__init__.py
+++ b/script/scaffold/templates/config_flow/integration/__init__.py
@@ -2,7 +2,6 @@
 from __future__ import annotations
 
 import asyncio
-from typing import Any
 
 from homeassistant.config_entries import ConfigEntry
 from homeassistant.core import HomeAssistant
@@ -14,11 +13,6 @@ from .const import DOMAIN
 PLATFORMS = ["light"]
 
 
-async def async_setup(hass: HomeAssistant, config: dict[str, Any]) -> bool:
-    """Set up the NEW_NAME component."""
-    return True
-
-
 async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
     """Set up NEW_NAME from a config entry."""
     # TODO Store an API object for your platforms to access
diff --git a/script/scaffold/templates/config_flow/tests/test_config_flow.py b/script/scaffold/templates/config_flow/tests/test_config_flow.py
index 8205fdbeda4..674cb921cdd 100644
--- a/script/scaffold/templates/config_flow/tests/test_config_flow.py
+++ b/script/scaffold/templates/config_flow/tests/test_config_flow.py
@@ -20,8 +20,6 @@ async def test_form(hass: HomeAssistant) -> None:
         "homeassistant.components.NEW_DOMAIN.config_flow.PlaceholderHub.authenticate",
         return_value=True,
     ), patch(
-        "homeassistant.components.NEW_DOMAIN.async_setup", return_value=True
-    ) as mock_setup, patch(
         "homeassistant.components.NEW_DOMAIN.async_setup_entry",
         return_value=True,
     ) as mock_setup_entry:
@@ -42,7 +40,6 @@ async def test_form(hass: HomeAssistant) -> None:
         "username": "test-username",
         "password": "test-password",
     }
-    assert len(mock_setup.mock_calls) == 1
     assert len(mock_setup_entry.mock_calls) == 1
 
 
diff --git a/script/scaffold/templates/config_flow_discovery/integration/__init__.py b/script/scaffold/templates/config_flow_discovery/integration/__init__.py
index 24a0c1d7350..6c187d1dafe 100644
--- a/script/scaffold/templates/config_flow_discovery/integration/__init__.py
+++ b/script/scaffold/templates/config_flow_discovery/integration/__init__.py
@@ -2,7 +2,6 @@
 from __future__ import annotations
 
 import asyncio
-from typing import Any
 
 from homeassistant.config_entries import ConfigEntry
 from homeassistant.core import HomeAssistant
@@ -14,11 +13,6 @@ from .const import DOMAIN
 PLATFORMS = ["light"]
 
 
-async def async_setup(hass: HomeAssistant, config: dict[str, Any]) -> bool:
-    """Set up the NEW_NAME component."""
-    return True
-
-
 async def async_setup_entry(hass: HomeAssistant, entry: ConfigEntry) -> bool:
     """Set up NEW_NAME from a config entry."""
     # TODO Store an API object for your platforms to access
diff --git a/tests/common.py b/tests/common.py
index 984b35716f0..32d2742f4d8 100644
--- a/tests/common.py
+++ b/tests/common.py
@@ -566,7 +566,7 @@ class MockModule:
         if platform_schema_base is not None:
             self.PLATFORM_SCHEMA_BASE = platform_schema_base
 
-        if setup is not None:
+        if setup:
             # We run this in executor, wrap it in function
             self.setup = lambda *args: setup(*args)
 
diff --git a/tests/components/airnow/test_config_flow.py b/tests/components/airnow/test_config_flow.py
index f7533b7f5ac..9937e899643 100644
--- a/tests/components/airnow/test_config_flow.py
+++ b/tests/components/airnow/test_config_flow.py
@@ -75,9 +75,7 @@ async def test_form(hass):
     assert result["type"] == data_entry_flow.RESULT_TYPE_FORM
     assert result["errors"] == {}
 
-    with patch("pyairnow.WebServiceAPI._get", return_value=MOCK_RESPONSE,), patch(
-        "homeassistant.components.airnow.async_setup", return_value=True
-    ) as mock_setup, patch(
+    with patch("pyairnow.WebServiceAPI._get", return_value=MOCK_RESPONSE), patch(
         "homeassistant.components.airnow.async_setup_entry",
         return_value=True,
     ) as mock_setup_entry:
@@ -90,7 +88,6 @@ async def test_form(hass):
 
     assert result2["type"] == data_entry_flow.RESULT_TYPE_CREATE_ENTRY
     assert result2["data"] == CONFIG
-    assert len(mock_setup.mock_calls) == 1
     assert len(mock_setup_entry.mock_calls) == 1
 
 
diff --git a/tests/components/deconz/test_config_flow.py b/tests/components/deconz/test_config_flow.py
index 8f9a597e00c..4380b8c6021 100644
--- a/tests/components/deconz/test_config_flow.py
+++ b/tests/components/deconz/test_config_flow.py
@@ -539,8 +539,6 @@ async def test_flow_hassio_discovery(hass):
     assert result["description_placeholders"] == {"addon": "Mock Addon"}
 
     with patch(
-        "homeassistant.components.deconz.async_setup", return_value=True
-    ) as mock_setup, patch(
         "homeassistant.components.deconz.async_setup_entry",
         return_value=True,
     ) as mock_setup_entry:
@@ -555,7 +553,6 @@ async def test_flow_hassio_discovery(hass):
         CONF_PORT: 80,
         CONF_API_KEY: API_KEY,
     }
-    assert len(mock_setup.mock_calls) == 1
     assert len(mock_setup_entry.mock_calls) == 1
 
 
diff --git a/tests/test_setup.py b/tests/test_setup.py
index c2cbc3d6ea8..9b68dbf4eab 100644
--- a/tests/test_setup.py
+++ b/tests/test_setup.py
@@ -3,7 +3,7 @@
 import asyncio
 import os
 import threading
-from unittest.mock import Mock, patch
+from unittest.mock import AsyncMock, Mock, patch
 
 import pytest
 import voluptuous as vol
@@ -618,3 +618,29 @@ async def test_async_get_loaded_integrations(hass):
         "myintegration",
         "device_tracker",
     }
+
+
+async def test_integration_no_setup(hass, caplog):
+    """Test we fail integration setup without setup functions."""
+    mock_integration(
+        hass,
+        MockModule("test_integration_without_setup", setup=False),
+    )
+    result = await setup.async_setup_component(
+        hass, "test_integration_without_setup", {}
+    )
+    assert not result
+    assert "No setup or config entry setup function defined" in caplog.text
+
+
+async def test_integration_only_setup_entry(hass):
+    """Test we have an integration with only a setup entry method."""
+    mock_integration(
+        hass,
+        MockModule(
+            "test_integration_only_entry",
+            setup=False,
+            async_setup_entry=AsyncMock(return_value=True),
+        ),
+    )
+    assert await setup.async_setup_component(hass, "test_integration_only_entry", {})