diff --git a/homeassistant/components/zeroconf/__init__.py b/homeassistant/components/zeroconf/__init__.py
index 6fd5d96a40c..fc87abd4bc1 100644
--- a/homeassistant/components/zeroconf/__init__.py
+++ b/homeassistant/components/zeroconf/__init__.py
@@ -5,6 +5,7 @@ import socket
 
 import voluptuous as vol
 from zeroconf import (
+    InterfaceChoice,
     NonUniqueNameException,
     ServiceBrowser,
     ServiceInfo,
@@ -20,6 +21,7 @@ from homeassistant.const import (
     __version__,
 )
 from homeassistant.generated.zeroconf import HOMEKIT, ZEROCONF
+import homeassistant.helpers.config_validation as cv
 
 _LOGGER = logging.getLogger(__name__)
 
@@ -34,12 +36,29 @@ ATTR_PROPERTIES = "properties"
 ZEROCONF_TYPE = "_home-assistant._tcp.local."
 HOMEKIT_TYPE = "_hap._tcp.local."
 
-CONFIG_SCHEMA = vol.Schema({DOMAIN: vol.Schema({})}, extra=vol.ALLOW_EXTRA)
+CONF_DEFAULT_INTERFACE = "default_interface"
+DEFAULT_DEFAULT_INTERFACE = False
+
+CONFIG_SCHEMA = vol.Schema(
+    {
+        DOMAIN: vol.Schema(
+            {
+                vol.Optional(
+                    CONF_DEFAULT_INTERFACE, default=DEFAULT_DEFAULT_INTERFACE
+                ): cv.boolean
+            }
+        )
+    },
+    extra=vol.ALLOW_EXTRA,
+)
 
 
 def setup(hass, config):
     """Set up Zeroconf and make Home Assistant discoverable."""
-    zeroconf = Zeroconf()
+    if config.get(CONF_DEFAULT_INTERFACE):
+        zeroconf = Zeroconf(interfaces=InterfaceChoice.Default)
+    else:
+        zeroconf = Zeroconf()
     zeroconf_name = f"{hass.config.location_name}.{ZEROCONF_TYPE}"
 
     params = {
diff --git a/tests/components/zeroconf/test_init.py b/tests/components/zeroconf/test_init.py
index a8e22e74bc4..eaa4c5ee61a 100644
--- a/tests/components/zeroconf/test_init.py
+++ b/tests/components/zeroconf/test_init.py
@@ -1,8 +1,9 @@
 """Test Zeroconf component setup process."""
 import pytest
-from zeroconf import ServiceInfo, ServiceStateChange
+from zeroconf import InterfaceChoice, ServiceInfo, ServiceStateChange
 
 from homeassistant.components import zeroconf
+from homeassistant.components.zeroconf import CONF_DEFAULT_INTERFACE
 from homeassistant.generated import zeroconf as zc_gen
 from homeassistant.setup import async_setup_component
 
@@ -78,6 +79,19 @@ async def test_setup(hass, mock_zeroconf):
     assert len(mock_config_flow.mock_calls) == expected_flow_calls
 
 
+async def test_setup_with_default_interface(hass, mock_zeroconf):
+    """Test default interface config."""
+    with patch.object(hass.config_entries.flow, "async_init"), patch.object(
+        zeroconf, "ServiceBrowser", side_effect=service_update_mock
+    ):
+        mock_zeroconf.get_service_info.side_effect = get_service_info_mock
+        assert await async_setup_component(
+            hass, zeroconf.DOMAIN, {zeroconf.DOMAIN: {CONF_DEFAULT_INTERFACE: True}}
+        )
+
+    assert mock_zeroconf.called_with(interface_choice=InterfaceChoice.Default)
+
+
 async def test_homekit_match_partial_space(hass, mock_zeroconf):
     """Test configured options for a device are loaded via config entry."""
     with patch.dict(