diff --git a/homeassistant/components/generic_thermostat/climate.py b/homeassistant/components/generic_thermostat/climate.py
index 2c27d371c5e..67d4be92c95 100644
--- a/homeassistant/components/generic_thermostat/climate.py
+++ b/homeassistant/components/generic_thermostat/climate.py
@@ -15,8 +15,12 @@ from homeassistant.components.climate.const import (
     HVAC_MODE_COOL,
     HVAC_MODE_HEAT,
     HVAC_MODE_OFF,
+    PRESET_ACTIVITY,
     PRESET_AWAY,
+    PRESET_COMFORT,
+    PRESET_HOME,
     PRESET_NONE,
+    PRESET_SLEEP,
     SUPPORT_PRESET_MODE,
     SUPPORT_TARGET_TEMPERATURE,
 )
@@ -64,10 +68,20 @@ CONF_COLD_TOLERANCE = "cold_tolerance"
 CONF_HOT_TOLERANCE = "hot_tolerance"
 CONF_KEEP_ALIVE = "keep_alive"
 CONF_INITIAL_HVAC_MODE = "initial_hvac_mode"
-CONF_AWAY_TEMP = "away_temp"
 CONF_PRECISION = "precision"
 SUPPORT_FLAGS = SUPPORT_TARGET_TEMPERATURE
 
+CONF_PRESETS = {
+    p: f"{p}_temp"
+    for p in (
+        PRESET_AWAY,
+        PRESET_COMFORT,
+        PRESET_HOME,
+        PRESET_SLEEP,
+        PRESET_ACTIVITY,
+    )
+}
+
 PLATFORM_SCHEMA = PLATFORM_SCHEMA.extend(
     {
         vol.Required(CONF_HEATER): cv.entity_id,
@@ -84,13 +98,12 @@ PLATFORM_SCHEMA = PLATFORM_SCHEMA.extend(
         vol.Optional(CONF_INITIAL_HVAC_MODE): vol.In(
             [HVAC_MODE_COOL, HVAC_MODE_HEAT, HVAC_MODE_OFF]
         ),
-        vol.Optional(CONF_AWAY_TEMP): vol.Coerce(float),
         vol.Optional(CONF_PRECISION): vol.In(
             [PRECISION_TENTHS, PRECISION_HALVES, PRECISION_WHOLE]
         ),
         vol.Optional(CONF_UNIQUE_ID): cv.string,
     }
-)
+).extend({vol.Optional(v): vol.Coerce(float) for (k, v) in CONF_PRESETS.items()})
 
 
 async def async_setup_platform(hass, config, async_add_entities, discovery_info=None):
@@ -110,7 +123,9 @@ async def async_setup_platform(hass, config, async_add_entities, discovery_info=
     hot_tolerance = config.get(CONF_HOT_TOLERANCE)
     keep_alive = config.get(CONF_KEEP_ALIVE)
     initial_hvac_mode = config.get(CONF_INITIAL_HVAC_MODE)
-    away_temp = config.get(CONF_AWAY_TEMP)
+    presets = {
+        key: config[value] for key, value in CONF_PRESETS.items() if value in config
+    }
     precision = config.get(CONF_PRECISION)
     unit = hass.config.units.temperature_unit
     unique_id = config.get(CONF_UNIQUE_ID)
@@ -130,7 +145,7 @@ async def async_setup_platform(hass, config, async_add_entities, discovery_info=
                 hot_tolerance,
                 keep_alive,
                 initial_hvac_mode,
-                away_temp,
+                presets,
                 precision,
                 unit,
                 unique_id,
@@ -156,7 +171,7 @@ class GenericThermostat(ClimateEntity, RestoreEntity):
         hot_tolerance,
         keep_alive,
         initial_hvac_mode,
-        away_temp,
+        presets,
         precision,
         unit,
         unique_id,
@@ -171,7 +186,7 @@ class GenericThermostat(ClimateEntity, RestoreEntity):
         self._hot_tolerance = hot_tolerance
         self._keep_alive = keep_alive
         self._hvac_mode = initial_hvac_mode
-        self._saved_target_temp = target_temp or away_temp
+        self._saved_target_temp = target_temp or next(iter(presets.values()), None)
         self._temp_precision = precision
         if self.ac_mode:
             self._hvac_list = [HVAC_MODE_COOL, HVAC_MODE_OFF]
@@ -187,12 +202,12 @@ class GenericThermostat(ClimateEntity, RestoreEntity):
         self._unit = unit
         self._unique_id = unique_id
         self._support_flags = SUPPORT_FLAGS
-        if away_temp:
+        if len(presets):
             self._support_flags = SUPPORT_FLAGS | SUPPORT_PRESET_MODE
-            self._attr_preset_modes = [PRESET_NONE, PRESET_AWAY]
+            self._attr_preset_modes = [PRESET_NONE] + list(presets.keys())
         else:
             self._attr_preset_modes = [PRESET_NONE]
-        self._away_temp = away_temp
+        self._presets = presets
 
     async def async_added_to_hass(self):
         """Run when entity about to be added."""
@@ -528,14 +543,15 @@ class GenericThermostat(ClimateEntity, RestoreEntity):
         if preset_mode == self._attr_preset_mode:
             # I don't think we need to call async_write_ha_state if we didn't change the state
             return
-        if preset_mode == PRESET_AWAY:
-            self._attr_preset_mode = PRESET_AWAY
-            self._saved_target_temp = self._target_temp
-            self._target_temp = self._away_temp
-            await self._async_control_heating(force=True)
-        elif preset_mode == PRESET_NONE:
+        if preset_mode == PRESET_NONE:
             self._attr_preset_mode = PRESET_NONE
             self._target_temp = self._saved_target_temp
             await self._async_control_heating(force=True)
+        else:
+            if self._attr_preset_mode == PRESET_NONE:
+                self._saved_target_temp = self._target_temp
+            self._attr_preset_mode = preset_mode
+            self._target_temp = self._presets[preset_mode]
+            await self._async_control_heating(force=True)
 
         self.async_write_ha_state()
diff --git a/tests/components/generic_thermostat/test_climate.py b/tests/components/generic_thermostat/test_climate.py
index a1896c94d2f..1720a54d973 100644
--- a/tests/components/generic_thermostat/test_climate.py
+++ b/tests/components/generic_thermostat/test_climate.py
@@ -13,8 +13,12 @@ from homeassistant.components.climate.const import (
     HVAC_MODE_COOL,
     HVAC_MODE_HEAT,
     HVAC_MODE_OFF,
+    PRESET_ACTIVITY,
     PRESET_AWAY,
+    PRESET_COMFORT,
+    PRESET_HOME,
     PRESET_NONE,
+    PRESET_SLEEP,
 )
 from homeassistant.components.generic_thermostat import (
     DOMAIN as GENERIC_THERMOSTAT_DOMAIN,
@@ -209,6 +213,10 @@ async def setup_comp_2(hass):
                 "heater": ENT_SWITCH,
                 "target_sensor": ENT_SENSOR,
                 "away_temp": 16,
+                "sleep_temp": 17,
+                "home_temp": 19,
+                "comfort_temp": 20,
+                "activity_temp": 21,
                 "initial_hvac_mode": HVAC_MODE_HEAT,
             }
         },
@@ -288,38 +296,73 @@ async def test_set_target_temp(hass, setup_comp_2):
     assert state.attributes.get("temperature") == 30.0
 
 
-async def test_set_away_mode(hass, setup_comp_2):
+@pytest.mark.parametrize(
+    "preset,temp",
+    [
+        (PRESET_NONE, 23),
+        (PRESET_AWAY, 16),
+        (PRESET_COMFORT, 20),
+        (PRESET_HOME, 19),
+        (PRESET_SLEEP, 17),
+        (PRESET_ACTIVITY, 21),
+    ],
+)
+async def test_set_away_mode(hass, setup_comp_2, preset, temp):
     """Test the setting away mode."""
     await common.async_set_temperature(hass, 23)
-    await common.async_set_preset_mode(hass, PRESET_AWAY)
+    await common.async_set_preset_mode(hass, preset)
     state = hass.states.get(ENTITY)
-    assert state.attributes.get("temperature") == 16
+    assert state.attributes.get("temperature") == temp
 
 
-async def test_set_away_mode_and_restore_prev_temp(hass, setup_comp_2):
+@pytest.mark.parametrize(
+    "preset,temp",
+    [
+        (PRESET_NONE, 23),
+        (PRESET_AWAY, 16),
+        (PRESET_COMFORT, 20),
+        (PRESET_HOME, 19),
+        (PRESET_SLEEP, 17),
+        (PRESET_ACTIVITY, 21),
+    ],
+)
+async def test_set_away_mode_and_restore_prev_temp(hass, setup_comp_2, preset, temp):
     """Test the setting and removing away mode.
 
     Verify original temperature is restored.
     """
     await common.async_set_temperature(hass, 23)
-    await common.async_set_preset_mode(hass, PRESET_AWAY)
+    await common.async_set_preset_mode(hass, preset)
     state = hass.states.get(ENTITY)
-    assert state.attributes.get("temperature") == 16
+    assert state.attributes.get("temperature") == temp
     await common.async_set_preset_mode(hass, PRESET_NONE)
     state = hass.states.get(ENTITY)
     assert state.attributes.get("temperature") == 23
 
 
-async def test_set_away_mode_twice_and_restore_prev_temp(hass, setup_comp_2):
+@pytest.mark.parametrize(
+    "preset,temp",
+    [
+        (PRESET_NONE, 23),
+        (PRESET_AWAY, 16),
+        (PRESET_COMFORT, 20),
+        (PRESET_HOME, 19),
+        (PRESET_SLEEP, 17),
+        (PRESET_ACTIVITY, 21),
+    ],
+)
+async def test_set_away_mode_twice_and_restore_prev_temp(
+    hass, setup_comp_2, preset, temp
+):
     """Test the setting away mode twice in a row.
 
     Verify original temperature is restored.
     """
     await common.async_set_temperature(hass, 23)
-    await common.async_set_preset_mode(hass, PRESET_AWAY)
-    await common.async_set_preset_mode(hass, PRESET_AWAY)
+    await common.async_set_preset_mode(hass, preset)
+    await common.async_set_preset_mode(hass, preset)
     state = hass.states.get(ENTITY)
-    assert state.attributes.get("temperature") == 16
+    assert state.attributes.get("temperature") == temp
     await common.async_set_preset_mode(hass, PRESET_NONE)
     state = hass.states.get(ENTITY)
     assert state.attributes.get("temperature") == 23